Giving Compass Take:
· Researchers at Rutgers University have identified 3 proteins in female mouse eggs that regulate each other in a way that doesn’t occur in any other healthy cell. This research may lead to new infertility and cancer treatments.
· What are the next steps in this research? How can funders help to drive research?
· Learn about supporting cancer research.
The unexpected complexity in how these proteins regulate one another doesn’t happen in any other healthy cell type, says Karen Schindler, an associate professor in the genetics department at Rutgers University-New Brunswick, who specializes in infertility research.
The three proteins are Aurora kinase A (AURKA), AURKB, and AURKC.
“Our research could provide a way to diagnose and perhaps treat certain types of infertility that end in early miscarriage,” says Schindler, senior author of the paper, which appears in Current Biology.
“This work also impacts cancer biology research because we suspect that the inter-protein regulation that occurs in eggs also occurs in certain types of aggressive cancers. Therefore, the findings could be useful in thinking about precision medicine treatments for cancer patients,” Schindler says.
Read the full article about infertility and cancer research by Todd Bates at Futurity.
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